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The NK-1R Antagonist Aprepitant Prevents LPS-Induced Oxidative Stress and Inflammation in RAW264.7 Macrophages

BACKGROUND: The macrophage is one of the most important types of immune cells that protect against harmful stimuli. Macrophage activation plays a pivotal role in the progression and development of various inflammatory diseases. The neurokinin 1 receptor (NK-1R) is a G protein-coupled receptor that p...

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Publicat a:Drug Des Devel Ther
Autors principals: Zhao, Xiao-nan, Bai, Zhen-zi, Li, Cheng-hua, Sheng, Chuan-lun, Li, Hong-yan
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246327/
https://ncbi.nlm.nih.gov/pubmed/32546961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S244099
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