PARP inhibitor olaparib sensitizes esophageal carcinoma cells to fractionated proton irradiation

Proton beam therapy (PBT) combined with chemotherapy, such as cis-diamminedichloroplatinum (II) (CDDP) and 5-fluorouracil (5-FU), has been employed as an alternative approach to improve clinical outcomes. PBT has been reported to be effective against esophageal cancer. However, apart from 5-FU and C...

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Detalhes bibliográficos
Publicado no:J Radiat Res
Main Authors: Kageyama, Shun-ichiro, Junyan, Du, Hojo, Hidehiro, Motegi, Atsushi, Nakamura, Masaki, Tsuchihara, Katsuya, Akimoto, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Regular Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246074/
https://ncbi.nlm.nih.gov/pubmed/31976528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrz088
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