Distinct anti-proliferative effects of herbal melanin on human acute monocytic leukemia THP-1 cells and embryonic kidney HEK293 cells

BACKGROUND: Herbal melanin (HM) is a dark pigment extracted from the seed coat of Nigella sativa L. and known to exert biological effects via toll-like receptor 4 (TLR4). Recently, TLR4 was described as involved in natural programmed cell death (apoptosis). Tumor and embryonic cells are used as in v...

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Veröffentlicht in:BMC Complement Med Ther
Hauptverfasser: El-Obeid, Adila, Alajmi, Hala, Harbi, Mashael, Yahya, Wesam Bin, Al-Eidi, Hamad, Alaujan, Monira, Haseeb, Adil, Trivilegio, Thadeo, Alhallaj, Alshaimaa, Alghamdi, Saleh, Ajlouni, Abdul-Wali, Matou-Nasri, Sabine
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245827/
https://ncbi.nlm.nih.gov/pubmed/32448225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-020-02944-1
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