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Elucidation of the Molecular Mechanisms Underlying Sorafenib-Induced Hepatotoxicity

Sorafenib is a small, orally-active multikinase inhibitor that is most frequently used for the management of renal cell carcinoma, hepatocellular carcinoma, and radioactive iodine-resistant thyroid carcinoma. However, recent reports have associated sorafenib with hepatotoxicity that can limit its cl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: AlAsmari, Abdullah F., Ali, Nemat, AlAsmari, Fawaz, AlAnazi, Wael A., Alqahtani, Faleh, Alharbi, Metab, Alotaibi, Farraj M., Aldossari, Abdullah A., AlSwayyed, Mohammed, Alanazi, Mohammed M., Alshamrani, Ali A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245685/
https://ncbi.nlm.nih.gov/pubmed/32509153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7453406
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