Molecular Insight into the Therapeutic Promise of Targeting APOE4 for Alzheimer's Disease

Alzheimer's disease (AD) is a progressive neurodegenerative disease that causes chronic cognitive dysfunction. Most of the AD cases are late onset, and the apolipoprotein E (APOE) isoform is a key genetic risk factor. The APOE gene has 3 key alleles in humans including APOE2, APOE3, and APOE4....

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Mamun, Abdullah Al, Uddin, Md. Sahab, Bin Bashar, Md. Fahim, Zaman, Sonia, Begum, Yesmin, Bulbul, Israt Jahan, Islam, Md. Siddiqul, Sarwar, Md. Shahid, Mathew, Bijo, Amran, Md. Shah, Md Ashraf, Ghulam, Bin-Jumah, May N., Mousa, Shaker A., Abdel-Daim, Mohamed M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245681/
https://ncbi.nlm.nih.gov/pubmed/32509144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5086250
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