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The 1α,25(OH)(2)D(3) Analogs ZK159222 and ZK191784 Show Anti-Inflammatory Properties in Macrophage-Induced Preadipocytes via Modulating the NF-κB and MAPK Signaling

PURPOSE: Key research findings suggest that attenuating metaflammation in adipose tissue might be a strategic step to prevent the metabolic syndrome and its associated disease outcomes. The anti-inflammatory effects of 1α,25(OH)(2)D(3) have been confirmed in our previous studies, but adverse effects...

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Veröffentlicht in:Diabetes Metab Syndr Obes
Hauptverfasser: Zhu, Jingjing, Wilding, John P H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245602/
https://ncbi.nlm.nih.gov/pubmed/32547133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S245080
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