Phosphodiesterase 4 inhibitors attenuate virus‐induced activation of eosinophils from asthmatics without affecting virus binding

Acute respiratory virus infections, such as influenza and RSV, are predominant causes of asthma exacerbations. Eosinophils act as a double‐edged sword in exacerbations in that they are activated by viral infections but also can capture and inactivate respiratory viruses. Phosphodiesterase type 4 (PD...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacol Res Perspect
Hauptverfasser: Sabogal Piñeros, Yanaika Shari, Dekker, Tamara, Smids, Barbara, Majoor, Christof J., Ravanetti, Lara, Villetti, Gino, Civelli, Maurizio, Facchinetti, Fabrizio, Lutter, René
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245579/
https://ncbi.nlm.nih.gov/pubmed/32447834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.557
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