BR-bodies provide selectively permeable condensates that stimulate mRNA decay and prevent release of decay intermediates

Biomolecular condensates play a key role in organizing RNAs and proteins into membraneless organelles. Bacterial RNP-bodies (BR-bodies) are a biomolecular condensate containing the RNA degradosome mRNA decay machinery, but the biochemical function of such organization remains poorly defined. Here we...

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Udgivet i:Mol Cell
Main Authors: Al-Husini, Nadra, Tomares, Dylan T., Pfaffenberger, Zechariah J., Muthunayake, Nisansala S., Samad, Mohammad A., Zuo, Tiancheng, Bitar, Obaidah, Aretakis, James R., Bharmal, Mohammed-Husain M., Gega, Alisa, Biteen, Julie S., Childers, W. Seth, Schrader, Jared M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245546/
https://ncbi.nlm.nih.gov/pubmed/32343944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.04.001
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