KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats

OBJECTIVE: The present study focused on the development of a poloxamer 407 thermosensitive hydrogel loaded with keratinocyte growth factor-2 (KGF-2) and fibroblast growth factor-21 (FGF-21) as a therapeutic biomaterial in a scald-wound model of type-2 diabetes in Goto-Kakizaki (GK) rats. RESEARCH DE...

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Vydáno v:BMJ Open Diabetes Res Care
Hlavní autoři: Yang, Xuanxin, Yang, Rongshuai, Chen, Min, Zhou, Qingde, Zheng, Yingying, Lu, Chao, Bi, Jianing, Sun, Wenzhe, Huang, Tongzhou, Li, Lijia, Gong, Jianxiang, Li, Xiaokun, Hui, Qi, Wang, Xiaojie
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2020
Témata:
Emerging Technologies, Pharmacology and Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245451/
https://ncbi.nlm.nih.gov/pubmed/32434772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-001009
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