Structural basis of nanobody recognition of grapevine fanleaf virus and of virus resistance loss

Grapevine fanleaf virus (GFLV) is a picorna-like plant virus transmitted by nematodes that affects vineyards worldwide. Nanobody (Nb)-mediated resistance against GFLV has been created recently, and shown to be highly effective in plants, including grapevine, but the underlying mechanism is unknown....

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Orlov, Igor, Hemmer, Caroline, Ackerer, Léa, Lorber, Bernard, Ghannam, Ahmed, Poignavent, Vianney, Hleibieh, Kamal, Sauter, Claude, Schmitt-Keichinger, Corinne, Belval, Lorène, Hily, Jean-Michel, Marmonier, Aurélie, Komar, Véronique, Gersch, Sophie, Schellenberger, Pascale, Bron, Patrick, Vigne, Emmanuelle, Muyldermans, Serge, Lemaire, Olivier, Demangeat, Gérard, Ritzenthaler, Christophe, Klaholz, Bruno P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245083/
https://ncbi.nlm.nih.gov/pubmed/32371486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913681117
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