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ARID1A prevents squamous cell carcinoma initiation and chemoresistance by antagonizing pRb/E2F1/c-Myc-mediated cancer stemness

Squamous cell carcinoma (SCC) is defined as a category of aggressive malignancies arising from the squamous epithelium of various organs. Resistance to chemotherapies is a common feature of SCCs, which leads to a poor prognosis among SCC patients. Recently, studies have illustrated the essential tum...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Luo, Qingyu, Wu, Xiaowei, Chang, Wan, Zhao, Pengfei, Nan, Yabing, Zhu, Xiaolin, Katz, Jonathan P., Su, Dan, Liu, Zhihua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244577/
https://ncbi.nlm.nih.gov/pubmed/31831874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0475-6
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