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Kinesin-14 motors drive a right-handed helical motion of antiparallel microtubules around each other

Within the mitotic spindle, kinesin motors cross-link and slide overlapping microtubules. Some of these motors exhibit off-axis power strokes, but their impact on motility and force generation in microtubule overlaps has not been investigated. Here, we develop and utilize a three-dimensional in vitr...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Mitra, Aniruddha, Meißner, Laura, Gandhimathi, Rojapriyadharshini, Renger, Roman, Ruhnow, Felix, Diez, Stefan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244531/
https://ncbi.nlm.nih.gov/pubmed/32444784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16328-z
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