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Leflunomide Inhibits Proliferation and Induces Apoptosis via Suppressing Autophagy and PI3K/Akt Signaling Pathway in Human Bladder Cancer Cells

INTRODUCTION: Bladder cancer is a lethal human malignancy. Currently, treatment for bladder cancer is limited. The anti-tumor effects of leflunomide have attracted much more concern in multiple human cancers. MATERIALS AND METHODS: This study evaluated the anti-tumor effects of leflunomide on cell v...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Cheng, Li, Wang, Hao, Wang, Zicheng, Huang, Houbao, Zhuo, Dong, Lin, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244359/
https://ncbi.nlm.nih.gov/pubmed/32546957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S252626
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