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Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation
Inflammation is an essential part of immunity against pathogens and tumors but can promote disease if not tightly regulated. Self and non-self-nucleic acids can trigger inflammation, through recognition by the cyclic GMP-AMP (cGAMP) synthetase (cGAS) and subsequent activation of the stimulator of in...
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| Vydáno v: | Sci Adv |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Association for the Advancement of Science
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244319/ https://ncbi.nlm.nih.gov/pubmed/32494729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax3333 |
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