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Frequency-Dependent Block of Excitatory Neurotransmission by Isoflurane via Dual Presynaptic Mechanisms

Volatile anesthetics are widely used for surgery, but neuronal mechanisms of anesthesia remain unidentified. At the calyx of Held in brainstem slices from rats of either sex, isoflurane at clinical doses attenuated EPSCs by decreasing the release probability and the number of readily releasable vesi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wang, Han-Ying, Eguchi, Kohgaku, Yamashita, Takayuki, Takahashi, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244188/
https://ncbi.nlm.nih.gov/pubmed/32327530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2946-19.2020
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