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Olaparib and Enzalutamide synergistically suppress HCC progression via the AR-mediated miR-146a-5p/BRCA1 signaling

Hepatocellular carcinoma (HCC) is one of most common cancers worldwide, however, the treatment for advanced HCC remains unsatisfactory. We focused on the function of the androgen receptor (AR) in HCC and tried to find new treatment strategy based on antiandrogen Enzalutamide (Enz). Here we found tha...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Zhao, Jie, Sun, Yin, Lin, Hui, Chou, Fuju, Xiao, Yao, Jin, Ren’an, Cai, Xiujun, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243671/
https://ncbi.nlm.nih.gov/pubmed/32134529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201903045RR
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