Long-Term Intranasal Insulin Aspart: A Profile of Gene Expression, Memory, and Insulin Receptors in Aged F344 Rats

Intranasal insulin is a safe and effective method for ameliorating memory deficits associated with pathological brain aging. However, the impact of different formulations and the duration of treatment on insulin’s efficacy and the cellular processes targeted by the treatment remain unclear. Here, we...

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Pubblicato in:J Gerontol A Biol Sci Med Sci
Autori principali: Frazier, Hilaree N, Ghoweri, Adam O, Sudkamp, Emily, Johnson, Eleanor S, Anderson, Katie L, Fox, Grant, Vatthanaphone, Keomany, Xia, Mengfan, Lin, Ruei-Lung, Hargis-Staggs, Kendra E, Porter, Nada M, Pauly, James R, Blalock, Eric M, Thibault, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243593/
https://ncbi.nlm.nih.gov/pubmed/31180116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz105
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