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Allele-Specific Transcript Abundance: A Pilot Study in Healthy Centenarians

The genetic basis of healthy aging and longevity remains largely unexplained. One hypothesis as to why long-lived individuals do not appear to have a lower number of common-complex disease variants, is that despite carrying risk variants, they express disease-linked alleles at a lower level than the...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Tindale, Lauren C, Thiessen, Nina, Leach, Stephen, Brooks-Wilson, Angela R
Formato: Artigo
Idioma:Inglês
Publicado em: OXFORD UNIVERSITY PRESS 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243586/
https://ncbi.nlm.nih.gov/pubmed/31504207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz188
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