Pathogenic Role of PPARα Downregulation in Corneal Nerve Degeneration and Impaired Corneal Sensitivity in Diabetes

The purpose of this study was to investigate the protective role of peroxisome proliferator–activated receptor α (PPARα) against diabetic keratopathy and corneal neuropathy. Corneal samples were obtained from human donors with and without diabetes. Streptozotocin-induced diabetic rats and mice were...

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Détails bibliographiques
Publié dans:Diabetes
Auteurs principaux: Matlock, H. Greg, Qiu, Fangfang, Malechka, Volha, Zhou, Kelu, Cheng, Rui, Benyajati, Siribhinya, Whelchel, Amy, Karamichos, Dimitrios, Ma, Jian-xing
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2020
Sujets:
Complications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243299/
https://ncbi.nlm.nih.gov/pubmed/32213513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0898
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