Hyperuricemia Predisposes to the Onset of Diabetes via Promoting Pancreatic β-Cell Death in Uricase-Deficient Male Mice

Clinical studies have shown a link between hyperuricemia (HU) and diabetes, while the exact effect of soluble serum urate on glucose metabolism remains elusive. This study aims to characterize the glucose metabolic phenotypes and investigate the underlying molecular mechanisms using a novel spontane...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Lu, Jie, He, Yuwei, Cui, Lingling, Xing, Xiaoming, Liu, Zhen, Li, Xinde, Zhang, Hui, Li, Hailong, Sun, Wenyan, Ji, Aichang, Wang, Yao, Yin, Huiyong, Li, Changgui
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2020
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243290/
https://ncbi.nlm.nih.gov/pubmed/32312870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0704
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