Substantia Nigra Volume Dissociates Bradykinesia and Rigidity from Tremor in Parkinson’s Disease: A 7 Tesla Imaging Study

BACKGROUND: In postmortem analysis of late stage Parkinson’s disease (PD) neuronal loss in the substantial nigra (SN) correlates with the antemortem severity of bradykinesia and rigidity, but not tremor. OBJECTIVE: To investigate the relationship between midbrain nuclei volume as an in vivo biomarke...

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Detalhes bibliográficos
Publicado no:J Parkinsons Dis
Main Authors: Poston, Kathleen L., Ua Cruadhlaoich, Matthew A. I., Santoso, Laura F., Bernstein, Jeffrey D., Liu, Tian, Wang, Yi, Rutt, Brian, Kerchner, Geoffrey A., Zeineh, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2020
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242837/
https://ncbi.nlm.nih.gov/pubmed/32250317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-191890
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