The polymorphism rs975484 in the protein arginine methyltransferase 1 gene modulates expression of immune checkpoint genes in hepatocellular carcinoma

Protein arginine methyltransferase 1 (PRMT1) is a key regulator of hepatic immune responses. Recently, we reported that PRMT1 regulates the tumor immune response in hepatocellular carcinoma (HCC). Here we found that PRMT1 expression in human HCC correlates with that of programmed cell death 1 ligand...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Schonfeld, Michael, Zhao, Jie, Komatz, Amberly, Weinman, Steven A., Tikhanovich, Irina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2020
Aiheet:
Gene Regulation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242710/
https://ncbi.nlm.nih.gov/pubmed/32245889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013401
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