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Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model

The treatment of major depressive disorder (MDD) is still a challenge. In the search for novel antidepressants, glutamatergic neuromodulators have been investigated as possible fast-acting antidepressants. Innovative studies suggest that the purine cycle and/or the purinergic signaling can be dysreg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: de Almeida, Roberto Farina, Pocharski, Camila Barbosa, Rodrigues, Ana Lúcia S., Elisabetsky, Elaine, Souza, Diogo O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242421/
https://ncbi.nlm.nih.gov/pubmed/32439951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65300-w
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