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Computational Polypharmacology: a New Paradigm for Drug Discovery

INTRODUCTION: Over the past couple of years, the cost of drug development has sharply increased along with the high rate of clinical trial failures. Such increase in expenses is partially due to the inability of the “one drug – one target” approach to predict drug side effects and toxicities. To tac...

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Pubblicato in:Expert Opin Drug Discov
Autori principali: Chaudhari, Rajan, Tan, Zhi, Huang, Beibei, Zhang, Shuxing
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241838/
https://ncbi.nlm.nih.gov/pubmed/28067061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2017.1280024
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