Differential effects of aquaporin-4 channel inhibition on BOLD fMRI and diffusion fMRI responses in mouse visual cortex

The contribution of astrocytes to the BOLD fMRI and DfMRI responses in visual cortex of mice following visual stimulation was investigated using TGN-020, an aquaporin 4 (AQP4) channel blocker, acting as an astrocyte function perturbator. Under TGN-020 injection the amplitude of the BOLD fMRI respons...

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Bibliographic Details
Published in:PLoS One
Main Authors: Komaki, Yuji, Debacker, Clement, Djemai, Boucif, Ciobanu, Luisa, Tsurugizawa, Tomokazu, Bihan, Denis Le
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241787/
https://ncbi.nlm.nih.gov/pubmed/32437449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228759
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