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DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells

Helminths like Schistosoma mansoni release excretory/secretory (E/S) products that modulate host immunity to enable infection. Extracellular vesicles (EVs) are among these E/S products, yet molecular mechanisms and functionality of S. mansoni EV interaction with host immune cells is unknown. Here we...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Kuipers, Marije E., Nolte-‘t Hoen, Esther N.M., van der Ham, Alwin J., Ozir-Fazalalikhan, Arifa, Nguyen, D. Linh, de Korne, Clarize M., Koning, Roman I., Tomes, John J., Hoffmann, Karl F., Smits, Hermelijn H., Hokke, Cornelis H.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241508/
https://ncbi.nlm.nih.gov/pubmed/32489529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2020.1753420
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