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Antifibrotic therapy to normalize the tumor microenvironment

Most tumors develop abnormal fibrotic regions consisting of fibroblasts, immune cells, and a dense extracellular matrix (ECM) immersed in a viscous interstitial fluid, and an abundant fibrotic tumor microenvironment (TME) is associated with poor outcome of treatment. It has been hypothesized that th...

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Bibliografski detalji
Izdano u:J Transl Med
Glavni autori: Hauge, Anette, Rofstad, Einar K.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240990/
https://ncbi.nlm.nih.gov/pubmed/32434573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02376-y
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