Statin inhibits large hepatitis delta antigen-Smad3 -twist-mediated epithelial-to-mesenchymal transition and hepatitis D virus secretion

BACKGROUND: Hepatitis D virus (HDV) infection may induce fulminant hepatitis in chronic hepatitis B patients (CHB) or rapid progression of CHB to cirrhosis or hepatocellular carcinoma. There is no effective treatment for HDV infection. HDV encodes small delta antigens (S-HDAg) and large delta antige...

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Bibliografiske detaljer
Udgivet i:J Biomed Sci
Main Authors: Liang, Yuh-Jin, Sun, Cheng-Pu, Hsu, Yu-Chen, Chen, Yi-Wen, Wang, I-An, Su, Chien-Wei, Tao, Mi-Hua, Wu, Jaw-Ching
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240974/
https://ncbi.nlm.nih.gov/pubmed/32434501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00659-6
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