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Development and optimization of orthotopic liver metastasis xenograft mouse models in uveal melanoma

BACKGROUND: Patients with metastatic uveal melanoma (MUM) in the liver usually die within 1 year. The development of new treatments for MUM has been limited by the lack of diverse MUM cell lines and appropriate animal models. We previously reported that orthotopic xenograft mouse models established...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Sugase, Takahito, Lam, Bao Q., Danielson, Meggie, Terai, Mizue, Aplin, Andrew E., Gutkind, J. Silvio, Sato, Takami
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240939/
https://ncbi.nlm.nih.gov/pubmed/32434572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02377-x
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