Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer

In vitro studies have suggested proteasome inhibitors could be effective in triple-negative breast cancer (TNBC). We found that bortezomib and carfilzomib induce proteotoxic stress and apoptosis via the unfolded protein response (UPR) in TNBC cell lines, with sensitivity correlated with expression o...

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Publicado no:Life Sci Alliance
Main Authors: Adwal, Alaknanda, Kalita-de Croft, Priyakshi, Shakya, Reshma, Lim, Malcolm, Kalaw, Emarene, Taege, Lucinda D, McCart Reed, Amy E, Lakhani, Sunil R, Callen, David F, Saunus, Jodi M
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240743/
https://ncbi.nlm.nih.gov/pubmed/32423906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900562
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