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Sex differences in the proliferation of pulmonary artery endothelial cells: implications for plexiform arteriopathy

The sex-biased disease pulmonary arterial hypertension (PAH) is characterized by the proliferation and overgrowth of dysfunctional pulmonary artery endothelial cells (PAECs). During inflammation associated with PAH, granzyme B cleaves intersectin-1 to produce N-terminal (EH(ITSN)) and C-terminal (SH...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Qin, Shanshan, Predescu, Dan N., Patel, Monal, Drazkowski, Patrick, Ganesh, Balaji, Predescu, Sanda A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240306/
https://ncbi.nlm.nih.gov/pubmed/32409569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.237776
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