Selective Survival of Sim1/MC4R Neurons in Diet-Induced Obesity

In the melanocortin pathway, melanocortin-4 receptor (MC4R) functions to control energy homeostasis. MC4R is expressed in a sub-population of Sim1 neurons (Sim1/MC4R neurons) and functions in hypothalamic paraventricular nuclei (PVN) to control food intake. Mapping sites of hypothalamic injury in ob...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Nyamugenda, Eugene, Griffin, Haven, Russell, Susan, Cooney, Kimberly A., Kowalczyk, Nicholas S., Islam, Ishrar, Phelan, Kevin D., Baldini, Giulia
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240135/
https://ncbi.nlm.nih.gov/pubmed/32438321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101114
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