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An Optimized Competitive-Aging Method Reveals Gene-Drug Interactions Underlying the Chronological Lifespan of Saccharomyces cerevisiae

The chronological lifespan of budding yeast is a model of aging and age-related diseases. This paradigm has recently allowed genome-wide screening of genetic factors underlying post-mitotic viability in a simple unicellular system, which underscores its potential to provide a comprehensive view of t...

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Vydáno v:Front Genet
Hlavní autoři: Avelar-Rivas, J. Abraham, Munguía-Figueroa, Michelle, Juárez-Reyes, Alejandro, Garay, Erika, Campos, Sergio E., Shoresh, Noam, DeLuna, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240105/
https://ncbi.nlm.nih.gov/pubmed/32477409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00468
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