Dedifferentiation of smooth muscle cells in intracranial aneurysms and its potential contribution to the pathogenesis

Smooth muscle cells (SMCs) are the major type of cells constituting arterial walls and play a role to maintain stiffness via producing extracellular matrix. Here, the loss and degenerative changes of SMCs become the major histopathological features of an intracranial aneurysm (IA), a major cause of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oka, Mieko, Shimo, Satoshi, Ohno, Nobuhiko, Imai, Hirohiko, Abekura, Yu, Koseki, Hirokazu, Miyata, Haruka, Shimizu, Kampei, Kushamae, Mika, Ono, Isao, Nozaki, Kazuhiko, Kawashima, Akitsugu, Kawamata, Takakazu, Aoki, Tomohiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239886/
https://ncbi.nlm.nih.gov/pubmed/32433495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65361-x
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