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Targeted pathological collagen delivery of sustained-release rapamycin to prevent heterotopic ossification

Heterotopic ossification (HO) in connective tissues like tendons and ligaments severely damages tissue structure. The pathogenesis of HO remains unclear but may involve mTOR. The results presented here indicate that tendon stem/progenitor cells do not undergo osteochondrogenic differentiation when m...

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Библиографические подробности
Опубликовано в: :Sci Adv
Главные авторы: Chen, Yangwu, Shen, Weiliang, Tang, Chenqi, Huang, Jiayun, Fan, Chunmei, Yin, Zi, Hu, Yejun, Chen, Weishan, Ouyang, Hongwei, Zhou, Yiting, Mao, Zhengwei, Chen, Xiao
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for the Advancement of Science 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239699/
https://ncbi.nlm.nih.gov/pubmed/32494667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9526
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