Identification of functional cis-acting RNA elements in the hepatitis E virus genome required for viral replication

There are approximately 20 million events of hepatitis E virus (HEV) infection worldwide annually. The genome of HEV is a single-strand, positive-sense RNA containing 5’ and 3’ untranslated regions and three open reading frames (ORF). HEV genome has 5’ cap and 3’ poly(A) tail to mimic host mRNA to e...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Ju, Xiaohui, Xiang, Guangtao, Gong, Mingli, Yang, Rui, Qin, Jierui, Li, Yafei, Nan, Yuchen, Yang, Yonglin, Zhang, Qiangfeng Cliff, Ding, Qiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239442/
https://ncbi.nlm.nih.gov/pubmed/32433693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008488
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