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Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis
The innate immune system fights infection with inflammasomes and interferons. Facultative bacterial pathogens that inhabit the host cytosol avoid inflammasomes(1–6) and are often insensitive to type I interferons (IFN-I), but are restricted by IFN-γ(7–11). However, it remains unclear how obligate cy...
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| Udgivet i: | Nat Microbiol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7239376/ https://ncbi.nlm.nih.gov/pubmed/32123346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-020-0673-5 |
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