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Rapid detection of SARS-CoV-2 by low volume real-time single tube reverse transcription recombinase polymerase amplification using an exo probe with an internally linked quencher (exo-IQ)

BACKGROUND: The current outbreak of SARS-CoV-2 has spread to almost every country with more than three million confirmed cases and over two hundred thousand deaths as of April 28, 2020. Rapid first-line testing protocols are needed for outbreak control and surveillance. METHODS: We used computationa...

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Publicat a:Clin Chem
Autors principals: Behrmann, Ole, Bachmann, Iris, Spiegel, Martin, Schramm, Marina, El Wahed, Ahmed Abd, Dobler, Gerhard, Dame, Gregory, Hufert, Frank T
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239256/
https://ncbi.nlm.nih.gov/pubmed/32384153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/clinchem/hvaa116
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