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A computational framework for distinguishing direct versus indirect interactions in human functional protein-protein interaction networks

Recognition of indirect interactions is instrumental to in silico reconstruction of signaling pathways and sheds light on the exploration of unknown physical paths between two indirectly interacting genes. However, very limited computational methods have explicitly exploited the indirect interaction...

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Bibliographic Details
Published in:Integr Biol (Camb)
Main Authors: Mei, Suyu, Flemington, Erik K., Zhang, Kun
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238765/
https://ncbi.nlm.nih.gov/pubmed/28524201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ib00013h
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