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Using a chimeric respiratory chain and EPR spectroscopy to determine the origin of semiquinone species previously assigned to mitochondrial complex I

BACKGROUND: For decades, semiquinone intermediates have been suggested to play an essential role in catalysis by one of the most enigmatic proton-pumping enzymes, respiratory complex I, and different mechanisms have been proposed on their basis. However, the difficulty in investigating complex I sem...

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發表在:BMC Biol
Main Authors: Wright, John J., Fedor, Justin G., Hirst, Judy, Roessler, Maxie M.
格式: Artigo
語言:Inglês
出版: BioMed Central 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238650/
https://ncbi.nlm.nih.gov/pubmed/32429970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00768-6
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