Co-culture of hWJMSCs and pACs in double biomimetic ACECM oriented scaffold enhances mechanical properties and accelerates articular cartilage regeneration in a caprine model

BACKGROUND: The dedifferentiation of chondrocytes and the unstable chondrogenic differentiation status of pluripotent mesenchymal stem cells (MSCs) are immense issues in cell-based articular cartilage repair and regenerative strategies. Here, to improve the cartilage characteristics of seed cells, a...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Zhang, Yu, Hao, Chunxiang, Guo, Weimin, Peng, Xiaoyu, Wang, Mingjie, Yang, Zhen, Li, Xu, Zhang, Xueliang, Chen, Mingxue, Sui, Xiang, Peng, Jiang, Lu, Shibi, Liu, Shuyun, Guo, Quanyi, Jiang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238567/
https://ncbi.nlm.nih.gov/pubmed/32430067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01670-2
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