Inhibition of LSD1 promotes the differentiation of human induced pluripotent stem cells into insulin-producing cells

BACKGROUND: Human induced pluripotent stem cells (hiPSCs) represent a potentially unlimited source of pancreatic endocrine lineage cells. Although insulin-producing β cells derived from hiPSCs have been successfully induced, much work remains to be done to achieve mature β cells. Lysine-specific dem...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Yang, Xiao-Fei, Zhou, Shu-Yan, Wang, Ce, Huang, Wei, Li, Ning, He, Fei, Li, Fu-Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238565/
https://ncbi.nlm.nih.gov/pubmed/32430053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01694-8
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