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SYBA: Bayesian estimation of synthetic accessibility of organic compounds

SYBA (SYnthetic Bayesian Accessibility) is a fragment-based method for the rapid classification of organic compounds as easy- (ES) or hard-to-synthesize (HS). It is based on a Bernoulli naïve Bayes classifier that is used to assign SYBA score contributions to individual fragments based on their freq...

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Publicat a:J Cheminform
Autors principals: Voršilák, Milan, Kolář, Michal, Čmelo, Ivan, Svozil, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238540/
https://ncbi.nlm.nih.gov/pubmed/33431015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-020-00439-2
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