Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress

INTRODUCTION: Alzheimer's disease (AD), the most common neurodegenerative disorder, is characterized by the accumulation of amyloid-β (Aβ) peptide and hyperphosphorylated tau protein. Accumulating evidence has revealed that the slow progressive deterioration of AD is associated with oxidative s...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Ren, Peng, Chen, Jingwei, Li, Bingxuan, Zhang, Mengzhou, Yang, Bei, Guo, Xiangshen, Chen, Ziyuan, Cheng, Hao, Wang, Pengfei, Wang, Shuaibo, Wang, Ning, Zhang, Guohua, Wu, Xu, Ma, Dan, Guan, Dawei, Zhao, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238335/
https://ncbi.nlm.nih.gov/pubmed/32454936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3050971
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