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Importance of Mesoporous Silica Particle Size in the Stabilization of Amorphous Pharmaceuticals—The Case of Simvastatin

In this paper, the role of mesoporous silica (MS) particle size in the stabilization of amorphous simvastatin (SVT) is revealed. For inhibiting recrystallization of the supercooled drug, the two MS materials (Syloid(®) XDP 3050 and Syloid(®) 244 FP) were employed. The crystallization tendency of SVT...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Knapik-Kowalczuk, Justyna, Kramarczyk, Daniel, Chmiel, Krzysztof, Romanova, Jana, Kawakami, Kohsaku, Paluch, Marian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238159/
https://ncbi.nlm.nih.gov/pubmed/32331310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040384
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