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Importance of Mesoporous Silica Particle Size in the Stabilization of Amorphous Pharmaceuticals—The Case of Simvastatin
In this paper, the role of mesoporous silica (MS) particle size in the stabilization of amorphous simvastatin (SVT) is revealed. For inhibiting recrystallization of the supercooled drug, the two MS materials (Syloid(®) XDP 3050 and Syloid(®) 244 FP) were employed. The crystallization tendency of SVT...
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| Vydáno v: | Pharmaceutics |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7238159/ https://ncbi.nlm.nih.gov/pubmed/32331310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040384 |
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