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PLGA Microspheres with Alginate-Coated Large Pores for the Formulation of an Injectable Depot of Donepezil Hydrochloride

As the main symptom of Alzheimer’s disease-related dementia is memory loss, patient compliance for donepezil hydrochloride (donepezil), administered as once-daily oral formulations, is poor. Thus, we aimed to design poly(lactic-co-glycolic acid) (PLGA) microspheres (MS) with alginate-coated large po...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Kim, Dohyun, Han, Tae Hee, Hong, Seong-Chul, Park, Sun Jae, Lee, Yong Hak, Kim, Hyeongmin, Park, Minwoo, Lee, Jaehwi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238133/
https://ncbi.nlm.nih.gov/pubmed/32244736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040311
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