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Oral Administration System Based on Meloxicam Nanocrystals: Decreased Dose Due to High Bioavailability Attenuates Risk of Gastrointestinal Side Effects

Meloxicam (MLX) is widely applied as a therapy for rheumatoid arthritis (RA); however, it takes far too long to reach its peak plasma concentration for a quick onset effect, and gastrointestinal toxicity has been observed in RA patients taking it. To solve these problems, we designed MLX solid nanop...

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Bibliografiska uppgifter
I publikationen:Pharmaceutics
Huvudupphovsmän: Nagai, Noriaki, Ogata, Fumihiko, Otake, Hiroko, Kawasaki, Naohito
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238067/
https://ncbi.nlm.nih.gov/pubmed/32244754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040313
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