An Interspecies Molecular and Functional Study of Organic Cation Transporters at the Blood-Brain Barrier: From Rodents to Humans

Organic cation transporters (OCTs) participate in the handling of compounds in kidneys and at the synaptic cleft. Their role at the blood-brain barrier (BBB) in brain drug delivery is still unclear. The presence of OCT1,2,3 (SLC22A1-3) in mouse, rat and human isolated brain microvessels was investig...

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Dettagli Bibliografici
Pubblicato in:Pharmaceutics
Autori principali: Chaves, Catarina, Campanelli, Federica, Chapy, Hélène, Gomez-Zepeda, David, Glacial, Fabienne, Smirnova, Maria, Taghi, Meryam, Pallud, Johan, Perrière, Nicolas, Declèves, Xavier, Menet, Marie-Claude, Cisternino, Salvatore
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238036/
https://ncbi.nlm.nih.gov/pubmed/32231079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040308
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