Development of 20(S)-Protopanaxadiol-Loaded SNEDDS Preconcentrate Using Comprehensive Phase Diagram for the Enhanced Dissolution and Oral Bioavailability

In this study, we aimed to develop a 20(S)-protopanaxadiol (PPD)-loaded self-nanoemulsifying drug delivery system (SNEDDS) preconcentrate (PSP) using comprehensive ternary phase diagrams for enhanced solubility, physical stability, dissolution, and bioavailability. Capmul MCM C8 and Capryol 90 were...

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Vydáno v:Pharmaceutics
Hlavní autoři: Kim, Young Hoon, Kim, Yu Chul, Jang, Dong-Jin, Min, Kyoung Ah, Karmacharya, Jenisha, Nguyen, Thi-Thao-Linh, Maeng, Han-Joo, Cho, Kwan Hyung
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238006/
https://ncbi.nlm.nih.gov/pubmed/32326560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040362
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