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Strategies to Obtain Encapsulation and Controlled Release of Small Hydrophilic Molecules

The therapeutic effect of small hydrophilic molecules is limited by the rapid clearance from the systemic circulation or a local site of administration. The unsuitable pharmacokinetics and biodistribution can be improved by encapsulating them in drug delivery systems. However, the high-water solubil...

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Publicado en:Front Bioeng Biotechnol
Autores principales: Li, Qi, Li, Xiaosi, Zhao, Chao
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7237580/
https://ncbi.nlm.nih.gov/pubmed/32478055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00437
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